5 Simple Techniques For https://www.ceesdekker.net
5 Simple Techniques For https://www.ceesdekker.net
Blog Article
‘Of course, that's about suitable. I hunt for a Actual physical knowledge of Organic units within a base-up way. I do think you may distinguish 3 lines of investigation in my team in the mean time. The 1st concerns chromosome construction: How will you receive a metre-lengthy DNA polymer folded and organised in this type of microscopic mobile? We have now developed visualisation strategies that let us to check how, for instance, SMC proteins loop DNA (video clip on Youtube) so as to build up chromosomes.
Our team scientific tests bacterial cell division and it is aiming to represent a ‘base up biology’ in synthetic cells that may autonomously divide. Our main desire lies in cell division, chromatin structure, and spatial Command.
To be a human being, I hold the biblical assignment to examine and use everything in development for the advantage of my neighbour. I will not experience any conflict among faith and science. On the contrary, my religion stimulates me to try and do science, to be open-minded on earth.’
Since 2000, Dekker has shifted the key aim of his function toward biophysics where he scientific studies the Qualities of solitary biomolecules and cells utilizing the applications of nanotechnology. This modification of industry was driven by his fascination for your impressive operating of biological molecular structures, along with with the extensive-term perspective that a lot of exciting discoveries is usually envisioned in this area.[5] Existing traces of investigate in his biophysics team are during the parts of:[six]
That could be a desire of mine and we established to work by using a delectable dose of naivety. This can be a thing that will most likely yield stunning brings about the for a longer time expression, but that doesn't make a difference. You shouldn't only want to operate around the inquiries of tomorrow, but also within the inquiries of your day right after tomorrow.’
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en ceesdekker moleculen te kunnen meten.
Given that 2000 he moved to single-molecule biophysics and nanobiology, with research from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his analysis has centered on finding out cell division with microbes on chip, though his best curiosity is in the course of acknowledging artificial cells.
Your ePaper is looking forward to publication! By publishing your doc, the written content will likely be optimally indexed by Google by means of AI and sorted into the ideal class for over 500 million ePaper viewers on YUMPU.
2003, shown the main biosensors designed outside of a carbon nanotube; solved the construction and mechanism of DNA repair proteins; and discovery of a completely new system for fabricating stable-condition nanopores for DNA translocation
Pretty great, but that wasn’t seriously exactly where my fascination lay. I needed to pioneer and I had the sensation which was now not probable, since the most attention-grabbing elementary insights had previously been uncovered. But my industry had created a lot of remarkable new tools to measure personal molecules. I made a decision which i needed to use this to biology, to take a look at it from the Bodily viewpoint.’
An built-in microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
Afterwards we spoke yet again briefly for the reason that Dekker felt that our discussion of his faith swiftly grew to become purely philosophical, Whilst In addition it concretely assists him in his perform.
2008, first observation of protein-coated DNA translocation through nanopores; resolved the origin of the electrophoretic drive on DNA in nanopores; found out an important velocity raise of microtubules in electric powered fields; uncovered an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of noise in carbon nanotubes in liquid
Illustration (2) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim of the pore is highlighted in purple, along with a 3D rendering with the motion with the DNA rod is displayed.